To help you carry out your research projects and advise you as best as possible in your approach, we offer to answer your biological questions thanks to the mastery of a set of specific proteomics technologies. Our experience allows the most appropriate use possible, in the context of your research projects, of an array of techniques:
Sample preparation:
- Total protein extraction
- Fractionation of complex samples (1D electrophoresis, UPLC, Liquid vein IEF...)
- Protein separation and purification
- Enzymatic digestion(s)
Shotgun proteomics :
- Protein identification by nanoLC-MS/MS. Also used for the characterization and identification of proteins partners
Differential proteomics :
- Relative quantification by Label free mass spectrometry
Analysis of post-translational modifications:
- e.g., Phosphoproteome analysis
In situ proteomics :
MALDI imaging mass spectrometry on tissue cryosections for the in situ characterization of proteins or small molecules.